Dr LEE Carol - School of Biomedical Sciences, CUHK

Dr LEE Carol

Assistant Lecturer

B.Sc. Ph.D.

39436817

carollee@cuhk.edu.hk

610U, Choh-Ming Li Basic Medical Sciences Building

Biography:

Dr. LEE Carol (李家樂) obtained her B.Sc. in Molecular Biotechnology (First Class Honors) and Ph.D. in Surgery from The Chinese University of Hong Kong (CUHK). She then worked in the biopharmaceutical industry before returning to CUHK as a postdoctoral researcher in the School of Biomedical Sciences (SBS). Dr. Lee has strong expertise in molecular biology, cancer biology and therapeutics. Her research focuses on deciphering oncogenic drivers and developing novel precision medicine strategies, including targeted therapy and cell-based immunotherapy, particularly in the context of liver cancer and lung cancer. Dr. Lee is passionate about teaching, mentorship and science communication. She has served as an advisor to undergraduate FYP students and the CUHK iGEM team. She has also received awards in science communication contests and has organized and hosted various academic conferences. Her teaching interests cover pharmacology and physiology.

Teaching and Research Interests

Course coordinator – PHAR3420 and PHAR2410.
Pharmacology and physiology courses.
Cancer biology and therapeutics.

Selected Publications

Lee C, Chen X, Mu W, Tsui SKW. ARAF p.S214C mutation enhances sorafenib response in lung cancer. 2024 Korean Association for Lung Cancer International Conference. 2024. Conference Abstract – Best Poster Presentation Award.
Deng M, Cai H, He B, Guan R, Lee C, Guo R. Hepatic arterial infusion chemotherapy versus transarterial chemoembolization, potential conversion therapies for single huge hepatocellular carcinoma: a retrospective comparison study. International Journal of Surgery. 2023;10:1097.
Lee C, Chan SM, Yeung SF, Tsui SKW. Targeting ARAF p.S214C mutation with sorafenib in non-small cell lung cancer. 2023 Annual Meeting of the American Association for Cancer Research. 2023. Conference Abstract.
Deng M, Lei Q, Wang J, Lee C, Guan R, Li S, Wei W, Chen H, Zhong C, Guo R. Nomograms for predicting the recurrence probability and recurrence-free survival in patients with hepatocellular carcinoma after conversion hepatectomy based on hepatic arterial infusion chemotherapy: a multicenter, retrospective study. International Journal of Surgery. 2023;10:1097.
Lee C, Chan SL, Chan WH, Cheung TT, Chong CN, Ng WC, Lai BS, Law HL, Li TC, Ng KC, Or YL, Yeung C, Xu MJ, Cheung ST. STAT3 regulates chemo-resistance and cancer stemness in hepatocellular carcinoma. 2020 Annual Meeting of the American Association for Cancer Research. 2020. Conference Abstract.
Lee C, Cheung ST. STAT3: An emerging therapeutic target for hepatocellular carcinoma. Cancers. 2019;11(11):1646.
Fung SW, Cheung PFY, Yip CW, Ng LWC, Cheung TT, Chong CCN, Lee C, Lai PBS, Chan AWH, Tsao GSW, Wong CH, Chan SL, Lo WS, Cheung ST. The ATP-binding cassette transporter ABCF1 is a hepatic oncofetal protein that promotes chemoresistance, EMT and cancer stemness in hepatocellular carcinoma. Cancer Letters. 2019;457:98-109.