Dr LEE Carol - School of Biomedical Sciences, CUHK

Dr LEE Carol

Assistant Lecturer

B.Sc. Ph.D.

39436817

carollee@cuhk.edu.hk

610U, Choh-Ming Li Basic Medical Sciences Building

Biography:

Dr. LEE Carol (李家樂) obtained her B.Sc. in Molecular Biotechnology (First Class Honors) and Ph.D. in Surgery from The Chinese University of Hong Kong (CUHK). Following her doctoral studies, she worked in the biopharmaceutical industry before rejoining CUHK as a postdoctoral researcher. She is currently an Assistant Lecturer in the School of Biomedical Sciences (SBS) in the Faculty of Medicine at CUHK. Dr. Lee has strong expertise in cancer biology and therapeutics, molecular biology and biotechnology. Her research focuses on deciphering oncogenic drivers and developing novel precision medicine strategies, including targeted therapy and cell-based immunotherapy, particularly in the context of liver cancer and lung cancer. Dr. Lee is passionate about teaching, mentorship and science communication. She has been an advisor to undergraduate students in science and medicine, providing support for their summer internships and thesis projects. She has also served as an instructor for the CUHK International Genetically Engineered Machine Competition (iGEM) team, and as a mentor at the Hong Kong Life Science Society (HKLSS). In addition, she has received awards in science communication contests and has organized and hosted several academic conferences. Her teaching interests cover pharmacology and physiology.

Teaching and Research Interests

Pharmacology and physiology education for health professions students
Course coordination – Pharmacology and Therapeutics I (PHAR2410)
Course coordination – Pharmacogenomics and Pharmaceutical Biotechnology (PHAR3420)
Cancer biology and therapeutics
Molecular biology and biotechnology
Use of digital game-based learning in medical education
Academic advising, mentorship and student support

Selected Publications

Lee, C., Mu, W., Chen, X.J., Chan, M.S.M., Chen, Z., Yeung, S.F., Chan, H.H.Y., Chow, S.T., Ko, B.C.B., Chan, D.W., Cho, W.C., & Tsui, S.K.W. (2025). Oncogenic activity and sorafenib sensitivity of ARAF p.S214C mutation in lung cancer. Cancers, 17(13), 2246.
Deng, M., Zhao, R., Zou, H., Guan, R., Wang, J., Lee, C., He, B., Zhou, J., Li, S., Wei, W., Cai, H., & Guo, R. (2025). Oxaliplatin induces pyroptosis in hepatoma cells and enhances antitumor immunity against hepatocellular carcinoma. British Journal of Cancer, 132(4), 371–383.
Lee, C., Chen, X., Mu, W., & Tsui, S.K.W. (2024). ARAF p.S214C mutation enhances sorafenib response in lung cancer. Korean Association for Lung Cancer International Conference 2024, Conference abstract.
Lee, C., & Tsui, S.K.W. (2024). Sorafenib sensitivity of ARAF p.S214C mutation in lung adenocarcinoma. HKU-CUHK Joint Postdoctoral Biomedical Sciences Symposium 2024, Conference abstract.
Deng M, Cai H, He B, Guan R, Lee, C., & Guo, R. (2023). Hepatic arterial infusion chemotherapy versus transarterial chemoembolization, potential conversion therapies for single huge hepatocellular carcinoma: A retrospective comparison study. International Journal of Surgery, 10, 1097.
Lee C., Chan, S.M., Yeung, S.F., & Tsui, S.K.W. (2023). Targeting ARAF p.S214C mutation with sorafenib in non-small cell lung cancer. Annual Meeting of the American Association for Cancer Research 2023, Conference abstract.
Deng M, Lei Q, Wang J, Lee C., Guan, R., Li, S., Wei, W., Chen, H., Zhong, C., & Guo, R. (2023). Nomograms for predicting the recurrence probability and recurrence-free survival in patients with hepatocellular carcinoma after conversion hepatectomy based on hepatic arterial infusion chemotherapy: A multicenter, retrospective study. International Journal of Surgery, 10, 1097.
Lee C., Chan, S.L., Chan, W.H., Cheung, T.T., Chong, C.N., Ng, W.C., Lai, B.S., Law, H.L., Li, T.C., Ng, K.C., Or, Y.L., Yeung, C., Xu, M.J., & Cheung, S.T. (2020). STAT3 regulates chemo-resistance and cancer stemness in hepatocellular carcinoma. Annual Meeting of the American Association for Cancer Research 2020, Conference abstract.
Lee C., & Cheung, S.T. (2019). STAT3: An emerging therapeutic target for hepatocellular carcinoma. Cancers, 11(11), 1646.
Fung, S.W., Cheung, P.F.Y., Yip, C.W., Ng, L.W.C., Cheung, T.T., Chong, C.C.N., Lee C., Lai, P.B.S., Chan, A.W.H., Tsao, G.S.W., Wong, C.H., Chan, S.L., Lo, W.S., & Cheung, S.T. (2019). The ATP-binding cassette transporter ABCF1 is a hepatic oncofetal protein that promotes chemoresistance, EMT and cancer stemness in hepatocellular carcinoma. Cancer Letters, 457, 98–109.

Awards

Best Poster Presentation Award & Travel Award, Korean Association for Lung Cancer International Conference, 2024.
Certificate of Presentation, HKU-CUHK Joint Postdoctoral Biomedical Sciences Symposium, 2024.
Certificate of Presentation, Annual Meeting of the American Association for Cancer Research, 2023.
PRINCE2 Practitioner Project Management Certification, AXELOS, 2022.
Certificate of Completion, course titled “Introduction to the Principles and Practice of Clinical Research (IPPCR)”, The National Institutes of Health (NIH), 2022.
Certificate of Presentation, Annual Meeting of the American Association for Cancer Research, 2020.
Cheng Tung Choy Postgraduate Award, The Chinese University of Hong Kong, 2017.
Video Favorite Award (Science Communication), FameLab Hong Kong, 2017.
Talent Development Scholarship for Science and Technology, HKSAR, 2015-2017.