张永成博士 – 生物醫學學院

张永成博士

Lecturer

39436894

dcheung@cuhk.edu.hk

610U, Choh-Ming Li Basic Medical Sciences Building, CUHK

个人简介

Dr. CHEUNG Wing Shing David (张永成) obtained his B.Sc. and Ph.D. degrees from The Chinese University of Hong Kong where his research initially focused on eye anatomy and later on developing novel drugs from natural products and herbal medicines for treating cardiovascular diseases, metabolic syndrome, and bacterial infections. Prior to joining the School of Biomedical Sciences, The Chinese University of Hong Kong, Dr. Cheung held research and academic posts in the tertiary education sector for more than eight years. He has extensive experience in teaching basic medical science subjects as well as curriculum design and management.

Teaching and Research Interests

Molecular Biology, Anatomy and Physiology Education
Novel Pharmacologic Treatments for Cardiovascular Diseases

Selected Publications

Cheung, D. W. S., Koon, C. M., Ng, C. F., Leung, P. C., Fung, K. P., Poon, S. K. S., & Lau, C. B. S. (2012). The roots of Salvia miltiorrhiza (Danshen) and Pueraria lobata (Gegen) inhibit atherogenic events: A study of the combination effects of the 2-herb formula. Journal of Ethnopharmacology, 143(3), 859–866.
Cheung, D. W. S., Koon, C. M., Wat, E., Ko, C. H., Chan, J. Y. W., Yew, D. T. W., Leung, P. C., Chan, W. Y., Lau, C. B. S., & Fung, K. P. (2013). A herbal formula containing roots of Salvia miltiorrhiza (Danshen) and Pueraria lobata (Gegen) inhibits inflammatory mediators in LPS-stimulated RAW 264.7 macrophages through inhibition of nuclear factor κb (NFκB) pathway. Journal of Ethnopharmacology, 145(3), 776–783.
Cheung, D. W. S., Koon, C. M., Wong, P. H., Yau, K. C., Wat, E., Hung, A. S. M., Wang, Y. P., Lau, K. M., Ko, C. H., Chan, J. Y. W., Waye, M. M. Y., & Fung, K. P. (2017). Evaluating Efficacy and Safety of Combination Medication of Atorvastatin and a Herbal Formula Containing Salvia miltiorrhiza and Pueraria lobata on Hyperlipidemia. Phytotherapy Research, 31(10), 1579–1589.
Cheung, D. W. S., Wai, M. S. M., & Yew, D. T. W. (2013). The diversity of cones in the retina of vertebrates: A review. OA Anatomy, 1(I), 1–6.
Caffino, L., Di Chio, M., Giannotti, G., Venniro, M., Mutti, A., Padovani, L., Cheung, D., Fumagalli, G. F., Yew, D. T., Fumagalli, F., & Chiamulera, C. (2015). The modulation of BDNF expression and signalling dissects the antidepressant from the reinforcing properties of ketamine: Effects of single infusion vs. chronic self-administration in rats. Pharmacological Research, 104, 22–30.
Chan, B. C. L., Dharmaratne, P., Wang, B., Lau, K. M., Lee, C. C., Cheung, D. W. S., Chan, J. Y. W., Yue, G. G. L., Lau, C. B. S., Wong, C. K., Fung, K. P., & Ip, M. (2021). Hypericin and Pheophorbide a Mediated Photodynamic Therapy Fighting MRSA Wound Infections: A Translational Study from In Vitro to In Vivo. Pharmaceutics, 13(9), 1399.
Chan, B. C. L., Han, X. Q., Lui, S. L., Wong, C. W., Wang, T. B. Y., Cheung, D. W. S., Cheng, S. W., Ip, M., Han, S. Q. B., Yang, X. S., Jolivalt, C., Lau, C. B. S., Leung, P. C., & Fung, K. P. (2015). Combating against methicillin-resistant Staphylococcus aureus—Two fatty acids from Purslane (Portulaca oleracea L.) exhibit synergistic effects with erythromycin. Journal of Pharmacy and Pharmacology, 67(1), 107–116.
Han, X. Q., Yue, G. L., Yue, R. Q., Dong, C. X., Chan, C. L., Ko, C. H., Cheung, D. W. S., Luo, K. W., Dai, H., Wong, C. K., Leung, P. C., & Han, Q. B. (2014). Structure elucidation and immunomodulatory activity of a beta glucan from the fruiting bodies of Ganoderma sinense. PLoS ONE, 9(2010).
Ko, C. H., Chau, L., Cheung, D. W. S., Koon, J. C. M., Fung, K. P., Leung, P. C., Poon, S. K., & Lau, C. B. S. (2014). An Innovative and Comprehensive Approach in Studying the Complex Synergistic Interactions Among Herbs in Chinese Herbal Formulae. In J. Poon & S. K. Poon (Eds.), Data Analytics for Traditional Chinese Medicine Research.
Ko, C. H., Lau, K. M., Chau, L., Cheung, D. W. S., Siu, W. S., Wong, H. L., Shum, W. T., Gao, S., Fung, K. P., Leung, P. C., Poon, S. K.-S., & Lau, C. B. S. (2016). Multitargeted combination effects of a triherbal formulation containing ELP against osteoporosis: In vitro evidence. Journal of Pharmacy and Pharmacology, 68(6), 826–833.
Koon, C. M., Cheung, D. W. S., Wong, P. H., Wat, E., Ng, S. K., Cheung, W. H., Lam, F. F. Y., Chook, P., Fung, K. P., Leung, P. C., & Yan, B. P. (2021). Salviae miltiorrhizae radix and puerariae lobatae radix herbal formula improves circulation, vascularization and gait function in a peripheral arterial disease rat model. Journal of Ethnopharmacology, 264, 113235.
Koon, C. M., Fong, S., Wat, E., Wang, Y. P., Cheung, D. W. S., Lau, C. B. S., Leung, P. C., Sun, H. D., Zhao, Q. S., & Fung, K. P. (2014). Mechanisms of the dilator action of the Erigerontis Herba on rat aorta. Journal of Ethnopharmacology, 155(3), 1561–1567.
Koon, C. M., Ko, C. H., Sun, X. X., Hoi, S. W. H., Tam, J. C. W., Cheung, D. W. S., Cheng, K. F., Pang, S. Y., Lo, W. M., Chook, P., Lau, C. B. S., Chan, W. Y., Leung, P. C., Kwok, T. C. Y., & Fung, K. P. (2013). Gene expression profiling on the molecular action of Danshen-Gegen formula in a randomized placebo-controlled trial of postmenopausal women with hypercholesterolemia. Evidence-Based Complementary and Alternative Medicine, 2013.
Ng, C. F., Koon, C. M., Cheung, D. W. S., Lam, M. Y., Leung, P. C., Lau, C. B. S., & Fung, K. P. (2011). The anti-hypertensive effect of Danshen (Salvia miltiorrhiza) and Gegen (Pueraria lobata) formula in rats and its underlying mechanisms of vasorelaxation. Journal of Ethnopharmacology, 137, 1366–1372.